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Dr.
Zhang is Professor of Epidemiology, and Director of
UCLA-USC Molecular Epidemiology Training Program at
University of California, Los Angeles. As a cancer
molecular epidemiologist, Dr. Zhang has studied gene-environment
interactions on the risk of a variety of cancers, especially
cigarette smoking and TP53 gene mutations on the risk
of bladder cancer,  marijuana
smoking and mutagen sensitivity on the risk of head
and neck cancer, green tea drinking and H. Pylori infection
on the risk of stomach cancer, tobacco smoking and
phases I and II as well as DNA repair genes on the
risk of lung cancer, alcohol drinking and susceptibility
genes on the risk of esophageal cancer.
Dr. Zhang's research interests focus on molecular genetic epidemiology
of cancers of the lung, bladder, prostate, esophagus, stomach, liver,
head and neck cancer, cervix, and AIDS-related malignancies. His research
team is working on mutations, methylations, and polymorphisms of tumor
suppresser genes such as TP53 and p16, of phases I and II genes, such
as GSTs, NATs, and CYP450s, and of DNA repair genes such as XRCC1. His
major focus of this research is to evaluate the main effects of these
genes on the risk of cancer and to assess potential gene-environment
interactions. Dr. Zhang is also interested in nutrition and cancer, epidemiology
of second primary cancers, methodological issues in the use of tumor
markers in cancer epidemiology, and the application of tumor markers
in progression and survival of cancer. He is the author of 114 articles
published in national and international scientific journals.
Dr. Zhang
has participated as a member of numerous NIH peer review
study sections. He has been a member of ACE since 1990
and a fellow since 1999 and he is a member of the Publication
Committee and was a member of the Education Committee.
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